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Diseases Treated

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Diseases Treated with Stem Cells

Many serious or life-threatening diseases have already been treated with cord blood. The following is a list of diseases that have been treated with cord blood and other sources of the same type of stem cell, like bone marrow.

Leukemias , Lymphomas and other Blood Cancers
  • Acute Biphenotypic Leukemia†
  • Acute Lymphocytic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Undifferentiated Leukemia†
  • Adult T Cell Leukemia/Lymphoma
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Hodgkin's Lymphoma
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Multiple Myeloma
  • Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia
  • Non-Hodgkin's Lymphoma
  • Prolymphocytic Leukemia
  • Plasma Cell Leukemia
  • Waldenstrom's Macroglobulinemia
Other Cancers
  • Brain Tumors††
  • Ewing Sarcoma†
  • Neuroblastoma
  • Ovarian Cancer††
  • Renal Cell Carcinoma††
  • Rhabdomyosarcoma
  • Small-Cell Lung Cancer††
  • Testicular Cancer††
  • Thymoma (Thymic Carcinoma)
Bone Marrow Failure Disorders
  • Amegakaryocytosis
  • Aplastic Anemia (Severe)
  • Blackfan-Diamond Anemia
  • Congenital Cytopenia†
  • Congenital Dyserythropoietic Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Pure Red Cell Aplasia
Hemoglobinopathies
  • Beta Thalassemia Major
  • Sickle Cell Disease
Histiocytic Disorders
  • Familial Erythrophagocytic Lymphohistiocytosis
  • Hemophagocytosis
  • Langerhans' Cell Histiocytosis (Histiocytosis X)
Myelodysplastic/Myeloproliferative Disorders
  • Acute Myelofibrosis†
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)†
  • Amyloidosis
  • Chronic Myelomonocytic Leukemia (CMML)
  • Essential Thrombocythemia†
  • Polycythemia Vera†
  • Refractory Anemias (RA) including:
    • Refractory Anemia with Excess Blasts (RAEB)
    • Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
    • Refractory Anemia with Ringed Sideroblasts (RARS)
Inherited Metabolic Disorders
  • Fucosidosis
  • Gaucher Disease†
  • Hunter Syndrome (MPS-II)
  • Hurler Syndrome (MPS-IH)
  • Krabbe Disease
  • Lesch-Nyhan Syndrome
  • Mannosidosis†
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Metachromatic Leukodystrophy
  • Mucolipidosis II (I-cell Disease)†
  • Neuronal Ceroid Lipofuscinosis (Batten Disease)†
  • Niemann-Pick Disease†
  • Sandhoff Disease†
  • Sanfilippo Syndrome (MPS-III)
  • Scheie Syndrome (MPS-IS)
  • Sly Syndrome (MPS-VII)
  • Tay Sachs†
  • Wolman Disease
Inherited Immune System Disorders
  • Chronic Granulomatous Disease
  • Congenital Neutropenia
  • Leukocyte Adhesion Deficiency
  • Severe Combined Immunodeficiencies (SCID) including:
    • Adenosine Deaminase Deficiency†
    • Bare Lymphocyte Syndrome
    • Chediak-Higashi Syndrome†
    • Kostmann Syndrome
    • Omenn Syndrome
    • Purine Nucleoside Phosphorylase Deficiency
    • Reticular Dysgenesis
  • Wiskott-Aldrich Syndrome
  • X-Linked Lymphoproliferative Disorder
Other Inherited Disorders
  • Cartilage-Hair Hypoplasia
  • Congenital Erythropoietic Porphyria (Gunther Disease)
  • DiGeorge Syndrome
  • Osteopetrosis
Other
  • Chronic Active Epstein Barr
  • Evans Syndrome
  • Multiple Sclerosis††
  • Rheumatoid Arthritis††
  • Systemic Lupus Erythematosus††
  • Thymic Dysplasia

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Source: Medical literature and clinicaltrials.gov.
†Refer to clinicaltrials.gov for additional information.
††Not routinely eligible for CBR's Designated Transplant Program®

Banking cord blood does not guarantee that the cells will provide a cure or be applicable for every situation. Ultimate use will be determined by the treating physician. The newborn may be able to use his or her cord blood for some of the conditions on this list, but not all. In some cases, a matched sibling's stem cells would be the first choice. Please consult your physician.